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At-home gut microbiome + metabolomic testing

Your gut has an answer.
We help you read it.

IBD, weight and metabolic health, GLP-1 response, inflammation, allergies, even the effects of smoking — they all leave a signature in your gut. RAW reads 200,000 microbial features and 200 metabolites and turns that signature into a plan you can act on.

200,000 microbial data points 200 unique metabolites $50 · everything included
Not tooth health. The mouth
This is about everything downstream.
The reframe

Your gut microbiome isn't a curiosity — it's a control system. It trains your immune cells, sets your inflammatory tone, tunes your metabolism, and shapes how you process every meal.

When that ecosystem drifts out of balance — dysbiosis — the effects surface far from the gut: bowel disease and flares, aching joints, stubborn weight, blood-sugar swings, allergies, and a low simmer of inflammation you can't quite explain. RAW measures the ecosystem itself, not just the symptoms it throws off.

Inflammatory bowel disease

Living with IBD, UC, or Crohn's? Your microbiome is half the story.

The IBD gut is a depleted ecosystem. Microbial diversity collapses. Anti-inflammatory workhorses like Faecalibacterium prausnitzii — a major producer of butyrate, the short-chain fatty acid that fuels and calms your gut lining — drop off, while inflammation-associated Proteobacteria expand to fill the gap. As the good actors fade, so does the butyrate that keeps the barrier intact.

  • Your diversity & balance, mapped against healthy reference profiles
  • The specific taxa — beneficial and inflammation-associated — shaping your gut right now
  • Your short-chain fatty acid & metabolite profile, including the butyrate your lining runs on
  • How it all shifts over time, so you can see what's actually helping

RAW doesn't diagnose IBD — your gastroenterologist does that. RAW gives you and your care team a molecular view a colonoscopy can't: who's living in your gut, what they're making, and how it changes between visits.

BALANCED · EUBIOSIS DIVERSITY BUTYRATE / SCFA Intact barrier DYSBIOSIS · IBD PATTERN DIVERSITY BUTYRATE / SCFA Thinned, leaky barrier
Balanced vs. dysbiotic gut — diversity, key taxa, and short-chain fatty acids. Illustrative.
The gut–body axis

Before it's arthritis. Your joints are listening to your gut.

Your gut doesn't stop at your gut. A leaky, dysbiotic community raises the systemic inflammation that drives disease elsewhere — and the shifts often show up early.

Joints. An early bloom of Prevotella copri has been repeatedly linked to new-onset rheumatoid arthritis, and gut-driven inflammation is fuel that autoimmune arthritis feeds on. The same short-chain fatty acids that calm your gut also help train the regulatory immune cells that keep autoimmunity in check.

  • Taxa & metabolites linked to systemic and joint inflammation
  • Where your gut sits relative to balanced reference profiles
  • The levers — often dietary — most likely to move it
YOUR GUT JointsPrevotella ↑ · inflammatory arthritis MetabolismAkkermansia ↓ · weight · insulin Immune toneSCFA ↓ · systemic inflammation
One ecosystem, body-wide effects. Associations shown are illustrative.
Metabolism · obesity · GLP-1

Weight is a whole-ecosystem problem. GLP-1 doesn't change that — it changes your gut.

Two of the biggest levers on your metabolic health live in your gut: the microbes that decide how much energy you pull from food, and the metabolites that tune your own appetite hormones. RAW reads both.

The gut behind the weight

The gut of someone carrying excess weight tends to look different: lower diversity, a shifted balance of major phyla, and fewer of the specialists tied to metabolic health — like Akkermansia muciniphila, a mucus-layer resident repeatedly associated with a leaner profile and a stronger gut barrier. When that barrier leaks, bacterial fragments (LPS) drive the low-grade "metabolic inflammation" that underlies insulin resistance. Your microbes also help set how many calories you actually absorb — and how satisfied you feel after a meal.

GLP-1 is made in your gut first

GLP-1 — the hormone behind Ozempic, Wegovy, Mounjaro and Zepbound — isn't only a drug. It's produced by your own intestinal L-cells, and its release is stimulated by the short-chain fatty acids your microbes make from fiber. A fiber-fed, SCFA-rich gut helps power your own GLP-1.

The relationship runs both ways. GLP-1 medications reshape the gut community — often increasing metabolism-friendly bacteria like Akkermansia — while the microbiome you start with may help explain why some people respond far more than others. There's a catch worth watching: because these drugs suppress appetite, some people eat so much less that microbial diversity drops, nudging the gut toward dysbiosis if nutrition isn't managed.

On GLP-1
Akkermansia ↑
Eating much less
Diversity ↓ risk
Your baseline
Linked to response
  • Metabolic-health taxa & diversity, benchmarked to reference profiles
  • Your SCFA profile — the fuel behind your own GLP-1 and gut barrier
  • A GLP-1 baseline & re-test to see whether your gut stays diverse and fiber-fed as your appetite changes
  • The dietary levers most likely to keep your metabolism working with the medication

On a GLP-1, or thinking about one? A before-and-after gut read shows whether the ecosystem that supports your metabolism is thriving — or thinning — as you eat less.

YOUR MICROBIOME GLP-1 APPETITE · GLUCOSE · WEIGHT Fiber → SCFAs stimulate your own GLP-1 GLP-1 meds reshape the gut Akkermansia ↑ · metabolism-friendly …but eating less can drop diversity
The gut ⇄ GLP-1 loop. Directions reflect current research; individual results vary.
Smoking · vaping · quitting

Smoking reaches all the way to your gut. Quitting shows up there too.

Cigarette smoke doesn't stop at the lungs. It reaches the gut, where it thins the protective mucus layer, stresses the barrier, and shifts the community — in some people toward a profile that resembles the inflamed, IBD-associated gut. Smoking is one of the clearest environmental factors known to modulate the gut microbiome, and it's a recognized risk factor for Crohn's disease.

Quitting tends to move things the other way. After cessation, studies have seen microbial diversity rise and the phylum balance shift — the same direction associated with better metabolic and cardiovascular markers. (Effect sizes vary between studies, and part of the shift tracks with the well-known post-quit weight change — which is itself partly a microbiome story.)

  • Where your gut sits relative to non-smoker reference profiles
  • Barrier- and inflammation-associated signals worth watching
  • A baseline to re-test after quitting and watch your gut recover

Trying to quit? A baseline now and a re-test in a few months turns an abstract health win into something you can actually see.

WHILE SMOKING DIVERSITY BARRIER / MUCUS Resembles IBD-associated pattern Proteobacteria ↑ · Crohn's risk factor AFTER QUITTING DIVERSITY BARRIER / MUCUS Diversity rises · phylum balance shifts Toward healthier metabolic markers
Smoking vs. post-cessation gut. Directional; effect sizes vary across studies.
Allergy · atopy · immune tolerance

Your immune system learned tolerance in your gut. It can lose it there too.

Most of your immune system lives around your gut, and it's trained by your microbes. A diverse microbiome — and the short-chain fatty acids it produces — teaches immune cells to tell harmless from harmful, largely by promoting regulatory T cells (Tregs) and a strong barrier that keeps stray antigens out of the bloodstream. Beneficial residents like Bifidobacterium and Lactobacillus are central to that education.

When diversity is low and the barrier is leaky — dysbiosis — that tolerance machinery weakens. Altered gut microbiota are consistently linked to allergic disease: food allergy, eczema, asthma, and other atopy. It's the modern edge of the "hygiene hypothesis," now measured in taxa and metabolites instead of guessed at.

  • Your microbial diversity — the raw material for immune tolerance
  • Your SCFA / butyrate profile — the signal that drives Tregs and barrier integrity
  • Tolerance-supporting taxa, and where yours stand

Allergies, eczema, or unexplained sensitivities? Your gut won't diagnose them — but it can show you the tolerance machinery underneath.

TOLERANCE Diversemicrobiome SCFAs(butyrate) Tregs +tight barrier Tolerance DYSBIOSIS → ALLERGY Lowdiversity ↓ SCFA · leakybarrier Allergic responseIgE · Th2 · atopy
How gut diversity and SCFAs shape immune tolerance vs. allergy. Illustrative.
Personalized nutrition

Does that food flare your microbiome? Now you can find out.

Diet reshapes the gut microbiome within days — for better or worse. Fiber and polyphenols feed the microbes that make anti-inflammatory short-chain fatty acids. Ultra-processed foods and common emulsifiers can thin your gut's protective mucus and tip the community toward inflammation.

But triggers are personal. The meal that calms one gut can flare another. RAW pairs your microbial and metabolite data to show which foods are likely fueling balance versus flare — for your gut, not a population average.

  • Calm vs. flare food guidance built from your own microbiome
  • The metabolic fingerprint of what you're eating now
  • Re-test after changes to confirm what's working
YOUR PLATE CalmsFiber · polyphenols → SCFA ↑ → balance FlaresUltra-processed · emulsifiers · your triggers
The same plate, two directions — decided by your microbiome. Illustrative.
The engine

One sample. 200,000 microbes. 200 metabolites.

Most tests count a handful of bacteria. RAW reads the whole community and what it's chemically producing — then translates it into something you can use.

01

Collect at home

A simple kit arrives at your door. Take your sample in minutes and ship it back — no clinic visit.

02

Deep sequencing

We profile the community down to the strain — every bug, not just the famous few.

200,000microbial features
03

Metabolomic panel

We measure what your microbes and body are making — from short-chain fatty acids to inflammatory markers.

200metabolites
04

Your report

We translate all of it into a clear picture and a personalized action plan — plus a version to share with your clinician.

What you get

A molecular read on your gut — in plain language.

Gut balance score

Where your ecosystem sits between eubiosis and dysbiosis, benchmarked against healthy references.

Key taxa

The beneficial and inflammation-associated species driving your gut — named, quantified, explained.

Metabolite profile

Your short-chain fatty acids and 200-metabolite panel — the chemistry behind how you feel.

Personalized food guidance

Which foods your gut is likely to treat as calm versus flare — specific to your data.

Track over time

Re-test to see your gut respond to diet, GLP-1, quitting, or treatment — and prove what's moving the needle.

Clinician-ready

A shareable report that puts a molecular gut view in front of your GI, rheumatologist, or physician.

One price · everything included

The whole picture — for $50.

Complete gut microbiome + metabolome report
$50
One kit. One flat price. No subscription.
  • At-home collection kit + prepaid return shipping
  • Deep metagenomic sequencing — 200,000 microbial features
  • Full metabolomic panel — 200 metabolites
  • Your Gut Balance Score + diversity benchmark
  • Beneficial & inflammation-associated taxa, explained
  • Short-chain fatty acid & metabolite profile
  • Personalized calm-vs-flare food guidance
  • Condition context: IBD · metabolic/GLP-1 · inflammation · allergy · smoking
  • Clinician-ready PDF you can share
  • Re-test anytime to track change
Get your kit — $50 →
No upsells · no surprise lab fees · cancel-free
Questions

What people ask before testing.

What exactly do I get for $50?

Everything: an at-home collection kit with prepaid return shipping, deep metagenomic sequencing of 200,000 microbial features, a full 200-metabolite panel, and a personalized report — your Gut Balance Score, key taxa, metabolite profile, calm-vs-flare food guidance, and a clinician-ready PDF. One flat price, no subscription.

Is this a medical test? Can it diagnose IBD, arthritis, or allergies?

No. RAW provides wellness and educational insights into your microbiome and metabolites. It is not a diagnostic test and is not intended to diagnose, treat, cure, or prevent any disease. Conditions like IBD, ulcerative colitis, Crohn's, inflammatory arthritis, and allergies are diagnosed and managed by a qualified clinician — and your report is built to share with them.

What's the difference between the microbes and the metabolites?

The microbes tell you who is living in your gut — the composition and diversity of the community. The metabolites tell you what they're doing — the chemistry they and your body produce, like short-chain fatty acids. Most tests measure only the first. You need both to see how your gut is actually functioning.

I'm on a GLP-1 (Ozempic, Wegovy, Mounjaro, Zepbound). Is this useful?

Yes — arguably more so. GLP-1 medications reshape your gut community, and because they suppress appetite, eating much less can lower microbial diversity if nutrition isn't managed. A baseline now and a re-test later show whether your gut is staying diverse and fiber-fed, and whether the ecosystem that supports your metabolism is working with the medication.

How do I collect the sample?

The kit walks you through a simple at-home collection that takes just a few minutes. Seal it, drop it in the prepaid mailer, and send it back to our lab. No appointment, no clinic.

Can I re-test to see whether changes are working?

Yes. Your gut responds to diet, medication, quitting smoking, and treatment — often within weeks. Re-test anytime and your report tracks the change over time, so you can see what's actually moving the needle rather than guessing.

How long until I get my results?

Turnaround runs from when your sample reaches the lab through sequencing, the metabolomic panel, and analysis — typically a few weeks. We'll email you the moment your report is ready.

Is my data private?

Your samples and results are yours.

Start reading your gut

Your gut has been trying to tell you something.

One at-home sample. 200,000 microbes and 200 metabolites, read and translated into a plan you can act on this week — for $50.

Important: RAW tests provide wellness and educational insights into your microbiome and metabolites. They are not intended to diagnose, treat, cure, or prevent any disease, and are not a substitute for professional medical advice, diagnosis, or treatment. Conditions such as IBD, ulcerative colitis, Crohn's disease, inflammatory arthritis, obesity, and allergic disease are diagnosed and managed by a qualified healthcare provider. Do not start, stop, or change any medication — including GLP-1 medications — or your smoking-cessation plan based on this report; talk with your physician.

Microbial and metabolic associations described here reflect current published research and are illustrative; the science is evolving and individual results vary. Statements on this page have not been evaluated by the FDA.